I look at views of healing among Brazilian Spiritists and medical professionals in a small city in the state of São Paulo, Brazil. In Brazil, esoteric praxis-knowledge, in the area of healing, blurs into mainstream religions and popular culture, and it stands in a complex relationship with allopathic medicine. The study is based on semi-structured interviews and participant observation with three groups of people: practicing Kardecists and Umbandists; allopathic medical professionals; and people who fall into both groups. The goal is to add nuances to CAS-E’s conception of ‘alternative rationalities.’ Issues addressed include (i) views of disease and healing, (ii) perceptions of the allopathic/esoteric divide and of relations between these divergent views of healing (e.g., tension, conflict, independence, complementarity), and (iii) the relevance of the Brazilian religious and social context (e.g., popular belief in spirits, healing-centred religiosity, strong tendencies to religious hybridity, and a trans-religious market religious services).